Theory of incompatible substructure problem

Schedule

• 1st December, 2014 : Submit final draft of Conformational Switching paper to Marco
• 22nd November, 2014 : Finish first draft of Conformational Switching paper
• 8th November, 2014 : Finalise results, create plots
• 1st November, 2014 : Finalise plan for experiments and collect preliminary data

Todo

• Outline by 8th November
• Mount existing container on shaker

Experiments

• Self-assembly experiment at different speeds:
  • Result: self-assembly time distribution for each speed; use in experiments speed with lowest average time to completion + 2 std. dev.
• 2 target structure
• 3 target structure
• 4 target structure
• 5 target structure

Particulars of experiments (10 trials each)

• Photos of initial condition and final condition
• Self-assembly experiment at different speeds:
  • Run each experiment till self-assembly of one, two, three and four target structures
  • Use different speeds starting from lowest speed (= when components start to move) and increment speed by 25 rpm till target structure breaks.
• Assembly of one target structure (Data to be collected: number of individual components, number of compatible substructures, number of incompatible substructures, number of targets)
• Results to show
  • Result 1
  • Result 2
  • Result 3
  • Result 4